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KMID : 1103920140200040398
Korean Journal of Hepatology
2014 Volume.20 No. 4 p.398 ~ p.401
Reversible splenial lesion on the corpus callosum in nonfulminant hepatitis A presenting as encephalopathy
Ko Soon-Young

Kim Byung-Kook
Kim Dong-Wook
Kim Jeong-Han
Choe Won-Hyeok
Seo Hee-Yeon
Kwon So-Young
Abstract
Reversible focal lesions on the splenium of the corpus callosum (SCC) have been reported in patients with mild encephalitis/encephalopathy caused by various infectious agents, such as influenza, mumps, adenovirus, Varicella zoster, Escherichia coli, Legionella pneumophila, and Staphylococcus aureus. We report a case of a reversible SCC lesion causing reversible encephalopathy in nonfulminant hepatitis A. A 30-year-old healthy male with dysarthria and fever was admitted to our hospital. After admission his mental status became confused, and so we performed electroencephalography (EEG) and magnetic resonance imaging (MRI) of the brain, which revealed an intensified signal on diffusion-weighted imaging (DWI) at the SCC. His mental status improved 5 days after admission, and the SCC lesion had completely disappeared 15 days after admission.
KEYWORD
Acute hepatitis A, Encephalopathy, Magnetic resonance imaging, Corpus callosum
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